The Prize
Call for application
Franco Regli Prize 2022/2023
Winner and distinguished nominee announced here
(Application closed on 20 January 2024)
Candidates are requested to send their scientific publication along with their CV to the email below. In addition, a hard copy must be sent to the postal address below. If a work is not yet published, but is accepted for publication, please attach the journal’s letter of acceptance.
Email: info@fondationfrancoregli.ch
Address:
Fondation Franco Regli
Maria Cristina Donati-Regli
Brunnadernstrasse 29
3006 Bern
Eligibility
The award addresses researchers whose excellent work significantly contributes to the understanding and treatment of neurodegenerative diseases.
All researchers may apply if a significant part of the research described in the publication has been conducted in Switzerland. Swiss researchers may submit work carried out abroad.
Both works in basic research and clinical research may be submitted.
The publication must be either published or accepted for publication in a peer-reviewed scientific journal.
The prize is awarded to the main author or the research team, in line with the guidelines of their institution.
All co-authors and institutions contributing to the publication may be mentioned by name in the written or verbal appraisal of the awarded research work.
The awardee is requested to present their awarded research.
Upon on recommendation by the scientific committee, the foundation committee may decide to award more than one research work for the prize.
In case no application qualifies for the prize, the prize may be cancelled or postponed to the following year.
Conditions
Awardees
Former awardees of the Franco Regli Prize
2020/2021
1st Prize: Dasha Elena Nelidova, for the work:
Dasha Nelidova, Rei K. Morikawa, Cameron S. Cowan, Zoltan Raics, David Goldblum, Hendrik P. N. Scholl, Tamas Szikra, Arnold Szabo, Daniel Hillier, Botond Roska, Restoring light sensitivity using tunable near-infrared sensors. Published 5 June 2020, Science 368, 1108 (2020) DOI: 10.1126/science.aaz5887
The three distinguished nominees are (in alphabetical order)
Fosco Bernasconi, Eva Blondiaux, for the work:
Bernasconi, E Blondiaux, J Potheegadoo, G Stripeikyte, J Pagonabarraga, H Bejr-Kasem, M Bassolino, M Akselrod, S Martinez-Horta, F Sampedro, M Hara, J Horvath, M Franza, S Konik, M Bereau, J-A Ghika, P.R Burkhard, D Van De Ville, N Faivre, G Rognini, P Krack, J Kulisevsky, O Blanke. Robot-induced hallucinations in Parkinson’s disease depend on altered sensorimotor processing in fronto-temporal network. Science Translational Medicine 28;13(591):eabc8362.
Annika Keller, for the work:
Y. Zarb, S. Sridhar, S. Nassiri, S. G. Utz, J. Schaffenrath, U. Maheshwari, E. J. Rushing, K.P. R Nilsson, M. Delorenzi, M. Colonna, M. Greter, A. Keller. Microglia control small vessel calcification via TREM2. Sci Adv. Feb 26;7(9):eabc4898(2021). doi: 10.1126/sciadv.abc4898. Print 2021 Feb. PMID: 33637522
Peter N. Nirmalraj, Thomas Schneider and Ansgar Felbecker, for the work:
Peter N. Nirmalraj, Thomas Schneider and Ansgar Felbecker, Spatial organisation of protein aggregates on RBCs as physical biomarkers of Alzheimer's disease pathology. Science Advances, 7, eabj2137, 2021.
2018/2019
1st Prize: Daniela Latorre and Ulf Kallweit, for the work:
Daniela Latorre, Ulf Kallweit, Eric Armentani, Mathilde Foglierini, Federico Mele, Antonino Cassotta, Sandra Jovic, David Jarrossay, Johannes Mathis, Francesco Zellini, Burkhard Becher, Antonio Lanzavecchia, Ramin Khatami, Mauro Manconi, Mehdi Tafti, Claudio l. Bassetti & Federica Sallusto. T cells in patients with narcolepsy target self-antigens of hypocretin neurons. Nature, October 2018, 562(7725): 63-68.
2nd Prize (ex aequo): Giovanni Di Liberto, for the work:
Giovanni Di Liberto, Stanislav Pantelyushin, Mario Kreutzfeldt, Nicolas Page, Stefano Musardo, Roland Coras, Karin Steinbach, Ilena Vincenti, Bogna Klimek, Thomas Lingner, Gabriela Salinas, Nathalie Lin-Marq,Ori Staszewski, Marta Joana Costa Jordaõ, Ingrid Wagner, Kristof Egervari, Matthias Mack, Camilla Bellone, Ingmar Blümcke, Marco Prinz, Daniel D. Pinschewer, and Doron Merkler. Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping. Cell 175, 4 October 2018, 1–14.
2nd Prize (ex aequo): Magdalini Polymenidou, for the work:
Florent Laferrière, Zuzanna Maniecka, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Larissa Gilhespy, Eva-Maria Hock, Ulrich Wagner, Tariq Afroz, Paul J. Boersema, Gery Barmettler, Sandrine C. Foti, Yasmine T. Asi, Adrian M. Isaacs, Ashraf Al-Amoudi, Amanda Lewis, Henning Stahlberg, John Ravits, Francesca De Giorgi, François Ichas, Erwan Bezard, Paola Picotti, Tammaryn Lashley and Magdalini Polymenidou. TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates. Nature Neuroscience, Vol. 22, January 2019, 65–77.
To read the research papers >
2016/2017
1st Prize: Dr. med Christian Barro, Clinique neurologique et policlinique, Département de médecine, bio-médecine et recherche clinique, Hôpital universitaire de Bâle et Université de Bâle, for the work:
Disanto G*, Barro C*, Benkert P*, Naegelin Y, Schädelin S, Giardiello A, Zecca C, Blennow K, Zetterberg H, Leppert D, Kappos L, Gobbi C, Kuhle J, et the Swiss Multiple Sclerosis Cohort Study Group. Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis. Ann Neurol, 2017, 81(6): 857-870. *equal contribution
2nd Prize: Prof. Dr. med. Caroline Pot and Dr. med. Aurélie Clottu, Département des neurosciences cliniques, Service de neurologie, CHUV, Lausanne, for the work:
Clottu A, Mathias A, Sailer AW, Schluep M, Seebach JD, Du Pasquier R, Pot C. EBI2 expression and function: robust in memory lymphocytes and increased by natalizumab in multiple sclerosis. Cell Rep. 3 January 2017,18(1): 213-224.
2013
Dr. Tiziana Sonati, Dr. Regina M. Reimann, Prof. Dr. Adriano Aguzzi, Institute of Neuropathology, University Hospital Zurich, for the work:
Tiziana Sonati, Regina M Reimann, Jeppe Falsig, Pravas Kumar Baral, Tracy O’Connor, Simone Hornemann, Sine Yaganoglu, Bei Li, Uli S. Herrmann, Barbara Wieland, Mridula Swayampakula, Muhammad Hafizur Rahman, Dipankar Das, Nat Kav, Roland Riek, Pawel P. Liberski, Michael N.G. James & Adriano Aguzzi. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 5 September 2013; 501(7465):102-6.
Dr. Paolo Paganetti, NSI/EOC-Laboratorio sperimentale, Bellinzona et Prof. Dr. Maurizio Molinari, Institute for Research in Biomedicine, Bellinzona, for the work:
Paolo Paganetti, Julia Reichwald, Dorothee Bleckmann, Dorothee Abramowski, Domenico Ammaturo, Carmen Barske, Simone Danner, Maurizio Molinari, Matthias Müller, Stéphane Papin, Sabine Rabe, Peter Schmid, Matthias Staufenbiel. Transgenic expression of β1 antibody in brain neurons impairs age-dependent amyloid deposition in APP23 mice. Neurobiology of Aging, 2013; 34(12):2866-78.
2010
Dr. Florence Clavaguera, Institut für Pathologie Universitätsspital Basel, for the work:
Clavaguera Florence, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology : 2009; 11:909-013.
PD Dr. méd. Andrea O. Rossetti, Service de neurologie CHUV, Lausanne, for the work:
Rossetti AO, Oddo M, Lagroscino G, Kaplan PW. Prognostication after cardiac arrest hypothermia. A prospective study. Ann Neurol: 2010;67:301-307.
2006
PhD Kilic Ertugrul, Neurologische Klinik Universitätspital Zürich, for the work:
Kilic E, Kilic Ü, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinisotol-3 kinase/Akt pathway mediates VEGEF’s neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J. 2006 Jun;20(8):1185-7.
Dr. Robert H. Andres, Depatment of Neurosurgery, University Hospital Berne, for the work:
Andres RH, Ducray AD, Huber AW, Pérez-Bouza A, Krebs SH, Schlattner U, Seiler RW, Wallimann T, Widmer HR. Effects of creatine treatment on survival and differentiation of GABA-ergic neurons in cultured striatal tissue. Journal of Neurochemistry, Wiley, 2005; 95:33-45.
2003
Dr. Fabienne Picard, Département des Neurosciences HUG, Genève, for the work :
Picard F, Bertrad D, Le Hellard S, Weiland S, Favre I, Philips H, Bertrand S, Berkovic SF, Malafosse A, Mullery J. How mutations in the nAChRs can cause ADNFLE Epilepsy. Epilepsia, 2002; 43 Suppl 5:112-22.
2002
Dr. Pierre Burkhard, Département des Neurosciences, HUG, Genève, for the work:
Burkhard P, Delavalle J, Du Pasquier R, Spahr L. Chronic parkinsonism associated with cirrhosis, Arch Neurology, 2003; 60: 521-528.
PD Dr. Hans H Jung, Neurologische Klinik Universitätspital Zürich, for the work:
Jung HH , Hergersberg M, Vogt M, Pahnke J, Treyer V, Röthlisberger B, Kollias SS, Russo D, Frwey BM. McLeod phenotype associated with a XK missense without hematological, neuromuscular or cerebral involvement. Journal of Transfusion.
Dr. Alexandre Croquelois, Service de neurologie, CHUV, Lausanne, for the work:
Croquelois A, Wintermark M, Reichert M, Meuli R, Bougousslavsky J. Stroke aphasia, the first 6 hours and after: a perfusion-CT and DWI correlation study. Annals of Neurology.
2001
Dr. David Winkler, Department of Neuropathology, Institute of Pathology University of Basel, for the work:
Winkler DT, Bondolfi L, Herzig MC, Jann L, Calhoun ME, Wiederhold KH, Tolnay M, Staufenbiel M, Jucker M. Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloïd angiopathy. J Neuroscience, 1 March 2001; 21(5):1619-1627